Botulinum Toxin Therapy for Laryngeal Dystonia(Spasmodic Dysphonia)

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Botulinum toxin injections for the treatment of spasmodic dysphonia.

BACKGROUND The use of botulinum toxin for the treatment of spasmodic dysphonia is currently the treatment of choice for management of this neurological voice disorder. Over the past 20 years, botulinum toxin has been used to treat both adductor and abductor forms of the disorder, with vocal improvement noted after treatment for both. A large number of studies have attempted to document the effi...

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Outcomes of botulinum toxin treatment for patients with spasmodic dysphonia.

BACKGROUND Spasmodic dysphonia (SD) is a focal dystonia of the larynx. Although individuals with SD have variable degrees of difficulty in everyday communication and speaking, many report significant impairments. The impact of SD on the quality of life of people with the disorder has not been well measured. OBJECTIVES To assess the impact of SD using a voice-specific, validated outcomes instr...

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Botulinum Toxin in Secondarily Nonresponsive Patients with Spasmodic Dysphonia.

Chemodenervation with botulinum toxin (BoNT) has been effective and well tolerated for all types of dystonia for >30 years. We reviewed outcomes of our patients treated with BoNT serotype A (BoNT-A) for spasmodic dysphonia (SD) who became secondarily nonresponsive. We found that 8 of 1400 patients became nonresponsive to BoNT-A (0.57%), which is lower than the secondary nonresponse rate in othe...

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Combined-modality treatment of adductor spasmodic dysphonia with botulinum toxin and voice therapy.

A combined-modality treatment program consisting of botulinum toxin injection (Botox) and voice therapy was used to treat 17 subjects diagnosed with adductor spasmodic dysphonia (ADD SD). Ten subjects with ADD SD served as the control and were given Botox only. Voice therapy after Botox injection was directed toward reducing the hyperfunctional vocal behaviors, primarily glottal overpressure at...

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Botulinum toxin therapy for cervical dystonia

Cervical dystonia, or torticollis, is perhaps the most common form of focal dystonia. The discovery that botulinum toxin was beneficial in the treatment of this disorder had a twofold impact. First, it silenced a small minority of physicians who believed that this disorder had a psychogenic basis despite convincing evidence to the contrary. Second, it alerted physicians to the broad potential o...

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ژورنال

عنوان ژورنال: Koutou (THE LARYNX JAPAN)

سال: 2018

ISSN: 0915-6127,2185-4696

DOI: 10.5426/larynx.30.72